Sunday, February 5, 2012

High Performance Partition Chromatography

High-Performance Partition Chromatography:  It is the most widely used liquid 
chromatographic procedures to separate most kinds of organic molecules. Here the 
components present in the analyte mixture distribute (or partition) themselves between the 
mobile phase and stationary phase as the  mobile phase moves through the column. The 
stationary phase actually consists of a thin liquid film either adsorbed or chemically bonded 
to the surface of finely divided solid particles. Of these the latter is considered more 
important and has a distinct stability advantage. It is not removed from the solid phase either 
by reaction or by heat and hence it is more popular. It finds wide applications in various 
fields, viz., pharmaceuticals, bio-chemicals, food products, industrial chemicals, pollutants, 
forensic chemistry, clinical medicine, etc. 

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