Wednesday, January 25, 2012

ANALYSIS THROUGH CHROMATOGRAPHY

ANALYSIS THROUGH CHROMATOGRAPHY 

The technique through which the chemical components present in complex mixtures are 
separated, identified and determined is termed as chromatography. This technique is widely 
used like spectroscopy and is a very powerful tool not only for analytical methods but also 
for preparative methods. Compounds of high grade purity can be obtained by this method. 
Chromatography can be simply defined as follows: 

It is the technique in which the components of a mixture are separated based upon the 
rates at which they are carried or moved through a stationary phase (column) by a gaseous 
or liquid mobile phase”.  


Based on the mobile phase this technique can be simply classified into two categories as: 
Liquid Chromatography and Gas Chromatography.  The column which holds the stationary 
phase (which in the form of small particles of the diameter of the order in microns), plays 
unique role in these processes. Usually silica is the base material for producing this phase.

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